Each drug can be used in combination with hormone therapy to treat hormone receptor-positive, HER2–negative metastatic breast cancers. Abemaciclib may also be used alone to treat these cancers. Other CDK4/6 inhibitors are under study for use in metastatic breast cancer treatment.
Frontline Treatments for Patients With Metastatic Breast Cancer. among patients with advanced ER-positive, HER2–negative metastatic breast cancer, though .
Estrogen receptor modulators and estrogen deprivation have become standards of care for hormone receptorâ€“ positive metastatic breast cancer. However, after .
Triple-negative breast cancers grow and spread more quickly than most other types of breast cancer. Because the cancer cells don't have hormone receptors, .
Breast cancer is the most commonly diagnosed malignancy and the second leading cause of cancer-related mortality among women in the US.1,2 .