Bone cancer is an unusual cancer that begins in a bone. Bone cancer can start in any bone within the physique, however it mostly impacts the lengthy bones that make up the legs and arms.
A number of forms of bone most cancers exist. Some forms of bone cancer happen primarily in youngsters, whereas others have an effect on principally adults.
The time period “bone most cancers” does not embrace cancers that start elsewhere within the physique and unfold (metastasize) to the bone. As a substitute, these cancers are named for the place they started, similar to breast most cancers that has metastasized to the bone.
Indicators and signs of bone most cancers embrace:
- Bone ache
- Swelling and tenderness close to the affected space
- Damaged bone
- Unintended weight reduction
When to see a health care provider
Make an appointment together with your physician if you happen to or your youngster develops indicators and signs that fear you.
It isn’t clear what causes most bone cancers. Medical doctors know bone most cancers begins as an error in a cell’s DNA. The error tells the cell to develop and divide in an uncontrolled means. These cells go on residing, relatively than dying at a set time. The accumulating mutated cells kind a mass (tumor) that may invade close by buildings or unfold to different areas of the physique.
Forms of bone most cancers
Bone cancers are damaged down into separate sorts primarily based on the kind of cell the place the most cancers started. The most typical forms of bone most cancers embrace:
- Osteosarcoma. Osteosarcoma begins within the bone cells. Osteosarcoma happens most frequently in youngsters and younger adults, within the bones of the leg or arm.
- Chondrosarcoma. Chondrosarcoma begins in cartilage cells. It normally happens within the pelvis, legs or arms in middle-aged and older adults.
- Ewing’s sarcoma. It isn’t clear the place in bone Ewing’s sarcoma begins, however the tumors mostly come up within the pelvis, legs or arms of youngsters and younger adults.
It isn’t clear what causes bone most cancers, however docs have discovered sure components are related to an elevated danger, together with:
- Inherited genetic syndromes. Sure uncommon genetic syndromes handed by households improve the chance of bone most cancers, together with Li-Fraumeni syndrome and hereditary retinoblastoma.
- Paget’s illness of bone. Mostly occurring in older adults, Paget’s illness of bone can improve the chance of bone most cancers growing later.
- Radiation remedy for most cancers. Publicity to massive doses of radiation, similar to these given throughout radiation remedy for most cancers, will increase the chance of bone most cancers sooner or later.