Between 2% to 5% of all colon cancers arise in the setting of well defined inherited syndromes, including Lynch syndrome, familial adenomatous polyposis , .
HEREDITARY COLORECTAL CANCERS. Hereditary colorectal cancers are associated with a specific inherited genetic abnormality.. Hereditary Non-Polyposis Colon Cancer, Lynch Syndrome (HNPCC). Familial Adenomatous Polyposis (FAP).
Inherited colorectal cancers are less common (about 5%) and occur when gene mutations, or changes, are passed within a family from 1 generation to the next .