Local immunotherapy with bacillus Calmette-GuÃ©rin (BCG) is an effective treatment to prevent recurrence and progression of superficial bladder cancer, but the antitumor mechanism of action of BCG remains unclear.
Though superficial bladder cancer patients have been treated with intravesical BCG since 1976 the mechanisms of action remain unknown. Evidence points towards an immune mechanism of BCG induced antitumor activity.
BCG is also used as a biotherapy for superficial bladder carcinoma. Despite being the most successful cancer biotherapy, the mechanism of action and .
Intravesical bacille Calmette-GuÃ©rin (BCG) has been used by urologists for several. understanding its exact mechanism of action, which is not fully understood.